750 MHz/89 mm Bruker Avance III HD

"750"

750 MHz/89 mm Bruker Avance III HD

MBI, AMRIS Facility, LG-123E

750 MHz NMR spectrometer

NMR experiments may be acquired using an Avance III HD spectrometer manufactured by Bruker Bio-Spin operating at a field strength of 17.6 tesla (750 MHz) with an 89mm bore. Spectroscopy data are collected using TopSpin software (version 3.6.1) while imaging data is collected with ParaVision 6.0.1.

MicroImaging

  • Micro-2.5 gradients (1500 mT/m)
  •  RF Coils – 5 / 10 / 15 / 20 / 25 / 30 mm
  • Mini 0.75 gradients (450 mT/m)
  • RF Coil – 33 mm
  •  Micro-5 gradients (3000 mT/m)
  • RF Coils – 5 /10 mm

Heteronuclear surface coils including 31P and 2H are available.

Solids

  • Low-E 4mm H/C
  • Low-E 3.2mm H/C/N

Diffusion

  • Diff 50 30 T/m Z-gradients
  • Proton/Carbon/Xenon/Fluorine 5 mm Single Resonance Coils

Spectroscopy

  • 5mm Triple-Resonance
  • 2.5mm Triple-Resonance

The 750 MHz system is suitable for imaging live rodents; mice in either the 30 or 33 mm coils, or small rats (<120 g) for head imaging in the 33 mm coils. A new gradient shielding setup has been implemented to significantly reduce artefacts previously seen from 4G/LTE interference.

Grant Acknowledgement

ALL PUBLICATIONS that include data obtained through MagLab (AMRIS) instrumentation, or involvement of MagLab-funded personnel at the AMRIS Facility, should acknowledge the corresponding NSF, NIH, and State of Florida grants that apply to instrumentation and usage time, in addition to the user’s project-specific funding sources.