Advanced Magnetic Resonance Imaging and Spectroscopy (AMRIS) Facility A National MagLab Facility at THE McKnight Brain Institute

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NMR-MRI/S: 5 T Dynamic Nuclear Polarization

MRI/S Systems Overview

3 T/70 cm Philips MR7700
3 T/60 cm Siemens Prisma
Retired: 4.7 T/33 cm Agilent VNMRS
7 T/20 cm Bruker BioSpec
11 T/40 cm Bruker Avance III HD
NMR-MRI/S: 5 T Dynamic Nuclear Polarization
600 MHz/51 mm Bruker Avance III
750 MHz/89 mm Bruker Avance III HD

NMR-MRI/S: 5 T Dynamic Nuclear Polarization

A scientist posing next to a D-N-P system.

Dynamic Nuclear Polarization (DNP):

AMRIS Facility’s dissolution DNP utilizes a 5 T magnet in which samples are cooled to <1.1 K. With microwave irradiation, we achieve 70% polarization of ¹³C nuclei in the polarizer; this translates to a >14,000 gain in SNR on dissolution and injection into an MRI/S scanner. The custom design of the polarizer enables the use of dissolution DNP to study metabolic flux in vivo using a variety of NMR–active nuclei as well as the study of fundamental mechanisms of polarization enhancement. This polarizer is available to external users through the MagLab.

Advanced Magnetic Resonance Imaging and Spectroscopy (AMRIS) Facility A National MagLab Facility at THE McKnight Brain Institute

Physical Address: Use GoogleMap at left, or send mail to:
PO Box 100015, Gainesville, FL 32610
Phone: 352-294-4995

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